Beta-defensin genomic copy number is not a modifier locus for cystic fibrosis

Human beta-defensin 2 (DEFB4, also known as DEFB2 or hBD-2) is a salt-sensitive antimicrobial protein that is expressed in lung epithelia. Previous work has shown that it is encoded in a cluster of beta-defensin genes at 8p23.1, which varies in copy number between 2 and 12 in different individuals....

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Detalles Bibliográficos
Autores principales: Hollox, Edward J, Davies, Jane, Griesenbach, Uta, Burgess, Juliana, Alton, Eric WFW, Armour, John AL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1318481/
https://www.ncbi.nlm.nih.gov/pubmed/16336654
http://dx.doi.org/10.1186/1477-5751-4-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1318481/
https://www.ncbi.nlm.nih.gov/pubmed/16336654
http://dx.doi.org/10.1186/1477-5751-4-9

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