Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells

Alcohol abuse reduces response rates to IFN therapy in patients with chronic hepatitis C. To model the molecular mechanisms behind this phenotype, we characterized the effects of ethanol on Jak-Stat and MAPK pathways in Huh7 human hepatoma cells, in HCV replicon cell lines, and in primary human hepa...

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Detalles Bibliográficos
Autores principales: Plumlee, Courtney R, Lazaro, Catherine A, Fausto, Nelson, Polyak, Stephen J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1318489/
https://www.ncbi.nlm.nih.gov/pubmed/16324217
http://dx.doi.org/10.1186/1743-422X-2-89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1318489/
https://www.ncbi.nlm.nih.gov/pubmed/16324217
http://dx.doi.org/10.1186/1743-422X-2-89

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