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Computational modeling reveals molecular details of epidermal growth factor binding
BACKGROUND: The ErbB family of receptors are dysregulated in a number of cancers, and the signaling pathway of this receptor family is a critical target for several anti-cancer drugs. Therefore a detailed understanding of the mechanisms of receptor activation is critical. However, despite a plethora...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322221/ https://www.ncbi.nlm.nih.gov/pubmed/16318625 http://dx.doi.org/10.1186/1471-2121-6-41 |