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Structural polymorphism of the HIV-1 leader region explored by computational methods

Experimental studies revealed that the elements of the human immunodeficiency virus type 1 (HIV-1) 5′-untranslated leader region (5′-UTR) can fold in vitro into two alternative conformations, branched (BMH) and ‘linearized’ (LDI) and switch between them to achieve different functionality. In this st...

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Detalles Bibliográficos
Autores principales: Kasprzak, Wojciech, Bindewald, Eckart, Shapiro, Bruce A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322270/
https://www.ncbi.nlm.nih.gov/pubmed/16371347
http://dx.doi.org/10.1093/nar/gki1015