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Structural polymorphism of the HIV-1 leader region explored by computational methods
Experimental studies revealed that the elements of the human immunodeficiency virus type 1 (HIV-1) 5′-untranslated leader region (5′-UTR) can fold in vitro into two alternative conformations, branched (BMH) and ‘linearized’ (LDI) and switch between them to achieve different functionality. In this st...
Autores principales: | Kasprzak, Wojciech, Bindewald, Eckart, Shapiro, Bruce A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322270/ https://www.ncbi.nlm.nih.gov/pubmed/16371347 http://dx.doi.org/10.1093/nar/gki1015 |
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