Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

The bulged insertions of (R)-1-O-(pyren-1-ylmethyl)glycerol (monomer P) in two complementary 8mer DNA strands (intercalating nucleic acids) opposite to each other resulted in the formation of an easily denaturing duplex, which had lower thermal stability (21.0°C) than the wild-type double-stranded D...

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Detalles Bibliográficos
Autores principales: Filichev, Vyacheslav V., Vester, Birte, Hansen, Lykke H., Pedersen, Erik B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322271/
https://www.ncbi.nlm.nih.gov/pubmed/16377781
http://dx.doi.org/10.1093/nar/gki1019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322271/
https://www.ncbi.nlm.nih.gov/pubmed/16377781
http://dx.doi.org/10.1093/nar/gki1019

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