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Using the TAP Component of the Antigen-Processing Machinery as a Molecular Adjuvant

We hypothesize that over-expression of transporters associated with antigen processing (TAP1 and TAP2), components of the major histocompatibility complex (MHC) class I antigen-processing pathway, enhances antigen-specific cytotoxic activity in response to viral infection. An expression system using...

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Detalles Bibliográficos
Autores principales: Vitalis, Timothy Z, Zhang, Qian-Jin, Alimonti, Judie, Chen, Susan S, Basha, Genc, Moise, Alex, Tiong, Jacqueline, Tian, Mei Mei, Choi, Kyung Bok, Waterfield, Douglas, Jeffries, Andy, Jefferies, Wilfred A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1323471/
https://www.ncbi.nlm.nih.gov/pubmed/16389301
http://dx.doi.org/10.1371/journal.ppat.0010036