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Characterization of a catalytically efficient acidic RNA-cleaving deoxyribozyme

We previously demonstrated—through the isolation of RNA-cleaving deoxyribozymes by in vitro selection that are catalytically active in highly acidic solutions—that DNA, despite its chemical simplicity, could perform catalysis under challenging chemical conditions [Liu,Z., Mei,S.H., Brennan,J.D. and...

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Detalles Bibliográficos
Autores principales: Kandadai, Srinivas A., Li, Yingfu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325019/
https://www.ncbi.nlm.nih.gov/pubmed/16391005
http://dx.doi.org/10.1093/nar/gki1013