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A novel Dictyostelium RasGEF required for chemotaxis and development

BACKGROUND: Ras proteins are guanine-nucleotide-binding enzymes that couple cell surface receptors to intracellular signaling pathways controlling cell proliferation and differentiation, both in lower and higher eukaryotes. They act as molecular switches by cycling between active GTP and inactive GD...

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Detalles Bibliográficos
Autores principales: Arigoni, Maddalena, Bracco, Enrico, Lusche, Daniel F, Kae, Helmut, Weeks, Gerald, Bozzaro, Salvatore
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325028/
https://www.ncbi.nlm.nih.gov/pubmed/16336640
http://dx.doi.org/10.1186/1471-2121-6-43