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Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides
BACKGROUND: MHC class I-peptide tetramers are currently utilised to characterize CD8(+ )T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4(+ )T cells appears less straightforward. Most MHC class II tetramers are produced with a homog...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325046/ https://www.ncbi.nlm.nih.gov/pubmed/16329759 http://dx.doi.org/10.1186/1471-2172-6-24 |