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Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides

BACKGROUND: MHC class I-peptide tetramers are currently utilised to characterize CD8(+ )T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4(+ )T cells appears less straightforward. Most MHC class II tetramers are produced with a homog...

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Detalles Bibliográficos
Autores principales: Moro, Monica, Cecconi, Virginia, Martinoli, Chiara, Dallegno, Eliana, Giabbai, Barbara, Degano, Massimo, Glaichenhaus, Nicholas, Protti, Maria Pia, Dellabona, Paolo, Casorati, Giulia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325046/
https://www.ncbi.nlm.nih.gov/pubmed/16329759
http://dx.doi.org/10.1186/1471-2172-6-24