Cargando…

Membrane TNF confers protection to acute mycobacterial infection

BACKGROUND: Tumour necrosis factor (TNF) is crucial for the control of mycobacterial infection as TNF deficient (KO) die rapidly of uncontrolled infection with necrotic pneumonia. Here we investigated the role of membrane TNF for host resistance in knock-in mice with a non-cleavable and regulated al...

Descripción completa

Detalles Bibliográficos
Autores principales: Fremond, Cecile, Allie, Nasiema, Dambuza, Ivy, Grivennikov, Sergei I, Yeremeev, Vladimir, Quesniaux, Valerie FJ, Jacobs, Muazzam, Ryffel, Bernhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325056/
https://www.ncbi.nlm.nih.gov/pubmed/16285886
http://dx.doi.org/10.1186/1465-9921-6-136