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Astrocyte reactivity to Fas activation is attenuated in TIMP-1 deficient mice, an in vitro study
BACKGROUND: Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a multifunctional secreted protein with pleiotropic actions, including the inhibition of matrix metalloproteinases (MMPs), cell death/survival and growth promoting activities. After inflammatory challenge, the levels of TIMP-1 are high...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325973/ https://www.ncbi.nlm.nih.gov/pubmed/16316466 http://dx.doi.org/10.1186/1471-2202-6-68 |