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Astrocyte reactivity to Fas activation is attenuated in TIMP-1 deficient mice, an in vitro study

BACKGROUND: Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a multifunctional secreted protein with pleiotropic actions, including the inhibition of matrix metalloproteinases (MMPs), cell death/survival and growth promoting activities. After inflammatory challenge, the levels of TIMP-1 are high...

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Detalles Bibliográficos
Autores principales: Ogier, Crystel, Creidy, Rita, Boucraut, José, Soloway, Paul D, Khrestchatisky, Michel, Rivera, Santiago
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325973/
https://www.ncbi.nlm.nih.gov/pubmed/16316466
http://dx.doi.org/10.1186/1471-2202-6-68