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Absence of mutations in the coding sequence of the potential tumor suppressor 3pK in metastatic melanoma
BACKGROUND: Activation of Ras or Raf contributes to tumorigenesis of melanoma. However, constitutive Raf activation is also a characteristic of the majority of benign melanocytic nevi and high intensity signaling of either Ras or Raf was found to induce growth inhibition and senescence rather than t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326198/ https://www.ncbi.nlm.nih.gov/pubmed/16367997 http://dx.doi.org/10.1186/1477-3163-4-23 |