Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease

BACKGROUND: Alzheimer's disease, a common dementia of the elder, is characterized by accumulation of protein amyloid deposits in the brain. Immunization to prevent this accumulation has been proposed as a therapeutic possibility, although adverse inflammatory reactions in human trials indicate...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Fonseca, Maria I, Kayed, Rakez, Hernandez, Irma, Webster, Scott D, Yazan, Ozkan, Cribbs, David H, Glabe, Charles G, Tenner, Andrea J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326209/
https://www.ncbi.nlm.nih.gov/pubmed/16332263
http://dx.doi.org/10.1186/1742-2094-2-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326209/
https://www.ncbi.nlm.nih.gov/pubmed/16332263
http://dx.doi.org/10.1186/1742-2094-2-28

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