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The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear

In mammals, six separate sensory regions in the inner ear are essential for hearing and balance function. Each sensory region is made up of hair cells, which are the sensory cells, and their associated supporting cells, both arising from a common progenitor. Little is known about the molecular mecha...

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Detalles Bibliográficos
Autores principales: Kiernan, Amy E, Xu, Jingxia, Gridley, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326221/
https://www.ncbi.nlm.nih.gov/pubmed/16410827
http://dx.doi.org/10.1371/journal.pgen.0020004