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Hypoxic stress suppresses RNA polymerase III recruitment and tRNA gene transcription in cardiomyocytes

RNA polymerase (pol) III transcription decreases when primary cultures of rat neonatal cardiomyocytes are exposed to low oxygen tension. Previous studies in fibroblasts have shown that the pol III-specific transcription factor IIIB (TFIIIB) is bound and regulated by the proto-oncogene product c-Myc,...

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Detalles Bibliográficos
Autores principales: Ernens, Isabelle, Goodfellow, Sarah J., Innes, Fiona, Kenneth, Niall S., Derblay, Louise E., White, Robert J., Scott, Pamela H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326236/
https://www.ncbi.nlm.nih.gov/pubmed/16407335
http://dx.doi.org/10.1093/nar/gkj402