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High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans
Telomerase is essential to maintain telomere length in most eukaryotes. Other functions for telomerase have been proposed but molecular mechanisms remain unclear. We studied Caenorhabditis elegans with a mutation in the trt-1 telomerase reverse transcriptase gene. Mutant animals showed a progressive...
Autores principales: | Cheung, Iris, Schertzer, Michael, Rose, Ann, Lansdorp, Peter M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326242/ https://www.ncbi.nlm.nih.gov/pubmed/16407328 http://dx.doi.org/10.1093/nar/gkj417 |
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