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Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice
BACKGROUND: Amiloride derivatives, commonly used for their diuretic and antihypertensive properties, can also cause a sustained but reversible decrease of intracellular pH (pH(i)). Using dimethyl amiloride (DMA) on normal rodent pancreatic islets, we previously demonstrated the critical influence of...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1327667/ https://www.ncbi.nlm.nih.gov/pubmed/16336655 http://dx.doi.org/10.1186/1472-6823-5-9 |