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Evolutionary programming as a platform for in silico metabolic engineering

BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both in terms of structure and regulation, it...

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Detalles Bibliográficos
Autores principales: Patil, Kiran Raosaheb, Rocha, Isabel, Förster, Jochen, Nielsen, Jens
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1327682/
https://www.ncbi.nlm.nih.gov/pubmed/16375763
http://dx.doi.org/10.1186/1471-2105-6-308