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Evolutionary programming as a platform for in silico metabolic engineering
BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both in terms of structure and regulation, it...
Autores principales: | Patil, Kiran Raosaheb, Rocha, Isabel, Förster, Jochen, Nielsen, Jens |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1327682/ https://www.ncbi.nlm.nih.gov/pubmed/16375763 http://dx.doi.org/10.1186/1471-2105-6-308 |
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