CaMKII tethers to L-type Ca(2+) channels, establishing a local and dedicated integrator of Ca(2+) signals for facilitation

Ca(2+)-dependent facilitation (CDF) of voltage-gated calcium current is a powerful mechanism for up-regulation of Ca(2+) influx during repeated membrane depolarization. CDF of L-type Ca(2+) channels (Ca(v)1.2) contributes to the positive force–frequency effect in the heart and is believed to involve...

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Detalles Bibliográficos
Autores principales: Hudmon, Andy, Schulman, Howard, Kim, James, Maltez, Janet M., Tsien, Richard W., Pitt, Geoffrey S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343528/
https://www.ncbi.nlm.nih.gov/pubmed/16275756
http://dx.doi.org/10.1083/jcb.200505155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343528/
https://www.ncbi.nlm.nih.gov/pubmed/16275756
http://dx.doi.org/10.1083/jcb.200505155

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