Mutation analysis of SDHB and SDHC: novel germline mutations in sporadic head and neck paraganglioma and familial paraganglioma and/or pheochromocytoma

BACKGROUND: Germline mutations of the SDHD, SDHB and SDHC genes, encoding three of the four subunits of succinate dehydrogenase, are a major cause of hereditary paraganglioma and pheochromocytoma, and demonstrate that these genes are classic tumor suppressors. Succinate dehydrogenase is a heterotetr...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Bayley, Jean-Pierre, van Minderhout, Ivonne, Weiss, Marjan M, Jansen, Jeroen C, Oomen, Peter HN, Menko, Fred H, Pasini, Barbara, Ferrando, Barbara, Wong, Nora, Alpert, Lesley C, Williams, Rosie, Blair, Edward, Devilee, Peter, Taschner, Peter EM
Format: Texto
Język:English
Wydane: BioMed Central 2006
Hasła przedmiotowe:
Research Article
Dostęp online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343542/
https://www.ncbi.nlm.nih.gov/pubmed/16405730
http://dx.doi.org/10.1186/1471-2350-7-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343542/
https://www.ncbi.nlm.nih.gov/pubmed/16405730
http://dx.doi.org/10.1186/1471-2350-7-1

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