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The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses

BACKGROUND: Tenofovir disoproxil fumarate, a prodrug of the nucleotide reverse transcriptase inhibitor, tenofovir (9-[9(R)-2-(phosphonomethoxy)propyl]adenine; PMPA), was recently approved for use in the combination therapy of human immunodeficiency virus (HIV)-1 infection. This study was undertaken...

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Detalles Bibliográficos
Autores principales: Anthonypillai, Christy, Gibbs, Julie E, Thomas, Sarah A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343584/
https://www.ncbi.nlm.nih.gov/pubmed/16390539
http://dx.doi.org/10.1186/1743-8454-3-1