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Desferrioxamine decreases NAD redox potential of intact red blood cells: evidence for desferrioxamine as an inducer of oxidant stress in red blood cells

BACKGROUND: Desferrioxamine (DFO) is an important iron chelating agent. It has also been thought of as an agent with anti-oxidant potential as it chelates ferric iron in various parts of the body. However, there is evidence suggesting that it may paradoxically affect red blood cells (RBC) by inducin...

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Detalles Bibliográficos
Autores principales: Niihara, Yutaka, Ge, Junli, Shalev, Oded, Wu, Huiyuan, Tu, Amy, Tanaka, Kouichi R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC134457/
https://www.ncbi.nlm.nih.gov/pubmed/12398791
http://dx.doi.org/10.1186/1472-6904-2-8