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Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand

BACKGROUND: Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce cytokines that direct T cell development. In particular, CD40L and IL-1 cooperatively activate DC to secrete high le...

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Detalles Bibliográficos
Autores principales: Wesa, Amy, Galy, Anne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC134468/
https://www.ncbi.nlm.nih.gov/pubmed/12385649
http://dx.doi.org/10.1186/1471-2172-3-14