Structure–function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog

Trl1 is an essential 827 amino acid enzyme that executes the end-healing and end-sealing steps of tRNA splicing in Saccharomyces cerevisiae. Trl1 consists of two domains—an N-terminal ligase component and a C-terminal 5′-kinase/2′,3′-cyclic phosphodiesterase (CPD) component—that can function in tRNA...

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Detalles Bibliográficos
Autores principales: Wang, Li Kai, Schwer, Beate, Englert, Markus, Beier, Hildburg, Shuman, Stewart
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345694/
https://www.ncbi.nlm.nih.gov/pubmed/16428247
http://dx.doi.org/10.1093/nar/gkj441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345694/
https://www.ncbi.nlm.nih.gov/pubmed/16428247
http://dx.doi.org/10.1093/nar/gkj441

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