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Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction

In vivo induction of the Escherichia coli lactose operon as a function of inducer concentration generates a sigmoidal curve, indicating a non-linear response. Suggested explanations for this dependence include a 2:1 inducer–repressor stoichiometry of induction, which is the currently accepted view....

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Detalles Bibliográficos
Autores principales: Oehler, Stefan, Alberti, Siegfried, Müller-Hill, Benno
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345695/
https://www.ncbi.nlm.nih.gov/pubmed/16432263
http://dx.doi.org/10.1093/nar/gkj453