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Unbiased in vitro selection reveals the unique character of the self-cleaving antigenomic HDV RNA sequence

In order to revisit the architecture of the catalytic center of the antigenomic hepatitis delta virus (HDV) ribozyme we developed an unbiased in vitro selection procedure that efficiently selected novel variants from a relatively small set of sequences. Using this procedure we examined all possible...

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Detalles Bibliográficos
Autores principales: Nehdi, Atef, Perreault, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345697/
https://www.ncbi.nlm.nih.gov/pubmed/16432262
http://dx.doi.org/10.1093/nar/gkj463