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The CD14 functional gene polymorphism -260 C>T is not involved in either the susceptibility to Chlamydia trachomatis infection or the development of tubal pathology

BACKGROUND: The functional polymorphism -260 C>T in the LPS sensing TLR4 co-receptor CD14 gene enhances the transcriptional activity and results in a higher CD14 receptor density. Individuals carrying the T/T genotype also have significantly higher serum levels of soluble CD14. The T allele of th...

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Detalles Bibliográficos
Autores principales: Ouburg, Sander, Spaargaren, Joke, den Hartog, Janneke E, Land, Jolande A, Fennema, Johan SA, Pleijster, Jolein, Peña, A Salvador, Morré, Servaas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351185/
https://www.ncbi.nlm.nih.gov/pubmed/16368002
http://dx.doi.org/10.1186/1471-2334-5-114