Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity

BACKGROUND: Autosomal recessive juvenile parkinsonism (AR-JP) is caused by mutations in the parkin gene which encodes an E3 ubiquitin-protein ligase. Parkin is thought to be critical for protecting dopaminergic neurons from toxic insults by targeting misfolded or oxidatively damaged proteins for pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez, Francisco A, Curtis, Wendy R, Palmiter, Richard D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351194/
https://www.ncbi.nlm.nih.gov/pubmed/16375772
http://dx.doi.org/10.1186/1471-2202-6-71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351194/
https://www.ncbi.nlm.nih.gov/pubmed/16375772
http://dx.doi.org/10.1186/1471-2202-6-71

Ejemplares similares