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The monoclonal antibody SM5-1 recognizes a fibronectin variant which is widely expressed in melanoma

BACKGROUND: Previously we have generated the monoclonal antibody SM5-1 by using a subtractive immunization protocol of human melanoma. This antibody exhibits a high sensitivity for primary melanomas of 99% (248/250 tested) and for metastatic melanoma of 96% (146/151 tested) in paraffin embedded sect...

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Detalles Bibliográficos
Autores principales: Trefzer, Uwe, Chen, Yingwen, Herberth, Gunda, Hofmann, Maja Ann, Kiecker, Felix, Guo, Yajun, Sterry, Wolfram
Formato: Texto
Lenguaje:English
Publicado: BioMed Central, 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351261/
https://www.ncbi.nlm.nih.gov/pubmed/16405722
http://dx.doi.org/10.1186/1471-2407-6-8