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A role for IgG immune complexes during infection with the intracellular pathogen Leishmania

We examined the role of immunoglobulin (Ig)G antibodies in mediating host defense to the intracellular parasite, Leishmania. We show that IgG not only fails to provide protection against this intracellular pathogen, but it actually contributes to disease progression. The J(H) strain of BALB/c mice,...

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Detalles Bibliográficos
Autores principales: Miles, Suzanne A., Conrad, Sean M., Alves, Renata G., Jeronimo, Selma M.B., Mosser, David M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351290/
https://www.ncbi.nlm.nih.gov/pubmed/15753208
http://dx.doi.org/10.1084/jem.20041470