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A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
We examined the role of immunoglobulin (Ig)G antibodies in mediating host defense to the intracellular parasite, Leishmania. We show that IgG not only fails to provide protection against this intracellular pathogen, but it actually contributes to disease progression. The J(H) strain of BALB/c mice,...
Autores principales: | Miles, Suzanne A., Conrad, Sean M., Alves, Renata G., Jeronimo, Selma M.B., Mosser, David M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351290/ https://www.ncbi.nlm.nih.gov/pubmed/15753208 http://dx.doi.org/10.1084/jem.20041470 |
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