Conditional Expression of Smad7 in Pancreatic β Cells Disrupts TGF-β Signaling and Induces Reversible Diabetes Mellitus

Identification of signaling pathways that maintain and promote adult pancreatic islet functions will accelerate our understanding of organogenesis and improve strategies for treating diseases like diabetes mellitus. Previous work has implicated transforming growth factor-β (TGF-β) signaling as an im...

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Detalles Bibliográficos
Autores principales: Smart, Nora G, Apelqvist, Åsa A, Gu, Xueying, Harmon, Erin B, Topper, James N, MacDonald, Raymond J, Kim, Seung K
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351925/
https://www.ncbi.nlm.nih.gov/pubmed/16435884
http://dx.doi.org/10.1371/journal.pbio.0040039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351925/
https://www.ncbi.nlm.nih.gov/pubmed/16435884
http://dx.doi.org/10.1371/journal.pbio.0040039

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