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Genomic Disorders: Molecular Mechanisms for Rearrangements and Conveyed Phenotypes

Rearrangements of our genome can be responsible for inherited as well as sporadic traits. The analyses of chromosome breakpoints in the proximal short arm of Chromosome 17 (17p) reveal nonallelic homologous recombination (NAHR) as a major mechanism for recurrent rearrangements whereas nonhomologous...

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Detalles Bibliográficos
Autores principales: Lupski, James R, Stankiewicz, Pawel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1352149/
https://www.ncbi.nlm.nih.gov/pubmed/16444292
http://dx.doi.org/10.1371/journal.pgen.0010049