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Computational Analysis and Prediction of the Binding Motif and Protein Interacting Partners of the Abl SH3 Domain
Protein-protein interactions, particularly weak and transient ones, are often mediated by peptide recognition domains, such as Src Homology 2 and 3 (SH2 and SH3) domains, which bind to specific sequence and structural motifs. It is important but challenging to determine the binding specificity of th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356089/ https://www.ncbi.nlm.nih.gov/pubmed/16446784 http://dx.doi.org/10.1371/journal.pcbi.0020001 |