Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles

The straightforward production and dose-controlled administration of protein therapeutics remain major challenges for the biopharmaceutical manufacturing and gene therapy communities. Transgenes linked to HIV-1-derived vpr and pol-based protease cleavage (PC) sequences were co-produced as chimeric f...

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Detalles Bibliográficos
Autores principales: Link, Nils, Aubel, Corinne, Kelm, Jens M., Marty, René R., Greber, David, Djonov, Valentin, Bourhis, Jean, Weber, Wilfried, Fussenegger, Martin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356536/
https://www.ncbi.nlm.nih.gov/pubmed/16449199
http://dx.doi.org/10.1093/nar/gnj014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356536/
https://www.ncbi.nlm.nih.gov/pubmed/16449199
http://dx.doi.org/10.1093/nar/gnj014

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