Pol II–Expressed shRNA Knocks Down Sod2 Gene Expression and Causes Phenotypes of the Gene Knockout in Mice

RNA interference (RNAi) has been used increasingly for reverse genetics in invertebrates and mammalian cells, and has the potential to become an alternative to gene knockout technology in mammals. Thus far, only RNA polymerase III (Pol III)–expressed short hairpin RNA (shRNA) has been used to make s...

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Detalles Bibliográficos
Autores principales: Xia, Xu-Gang, Zhou, Hongxia, Samper, Enrique, Melov, Simon, Xu, Zuoshang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1358942/
https://www.ncbi.nlm.nih.gov/pubmed/16450009
http://dx.doi.org/10.1371/journal.pgen.0020010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1358942/
https://www.ncbi.nlm.nih.gov/pubmed/16450009
http://dx.doi.org/10.1371/journal.pgen.0020010

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