A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames

CTL based vaccine strategies in the macaque model of AIDS have shown promise in slowing the progression to disease. However, rapid CTL escape viruses can emerge rendering such vaccination useless. We hypothesized that such escape is made more difficult if the immunizing CTL epitope falls within a re...

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Detalles Bibliográficos
Autores principales: Klase, Zachary, Donio, Michael J, Blauvelt, Andrew, Marx, Preston A, Jeang, Kuan-Teh, Smith, Stephen M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360091/
https://www.ncbi.nlm.nih.gov/pubmed/16398928
http://dx.doi.org/10.1186/1742-4690-3-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360091/
https://www.ncbi.nlm.nih.gov/pubmed/16398928
http://dx.doi.org/10.1186/1742-4690-3-1

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