C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells

BACKGROUND: The transcription factor, C/EBPbeta, is a key regulator of growth and differentiation in the mammary gland. There are three different protein isoforms of C/EBPbeta. C/EBPbeta-1 and -2 are transactivators, and differ by only 23 N-terminal amino acids present in beta-1 only. C/EBPbeta-3 (L...

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Detalles Bibliográficos
Autores principales: Bundy, Linda, Wells, Sam, Sealy, Linda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360092/
https://www.ncbi.nlm.nih.gov/pubmed/16371159
http://dx.doi.org/10.1186/1476-4598-4-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360092/
https://www.ncbi.nlm.nih.gov/pubmed/16371159
http://dx.doi.org/10.1186/1476-4598-4-43

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