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The selective Cox-2 inhibitor Celecoxib suppresses angiogenesis and growth of secondary bone tumors: An intravital microscopy study in mice

BACKGROUND: The inhibition of angiogenesis is a promising strategy for the treatment of malignant primary and secondary tumors in addition to established therapies such as surgery, chemotherapy, and radiation. There is strong experimental evidence in primary tumors that Cyclooxygenase-2 (Cox-2) inhi...

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Detalles Bibliográficos
Autores principales: Klenke, Frank Michael, Gebhard, Martha-Maria, Ewerbeck, Volker, Abdollahi, Amir, Huber, Peter E, Sckell, Axel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360103/
https://www.ncbi.nlm.nih.gov/pubmed/16409625
http://dx.doi.org/10.1186/1471-2407-6-9