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TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases
BACKGROUND: Airway remodeling in asthma is the result of increased expression of connective tissue proteins, airway smooth muscle cell (ASMC) hyperplasia and hypertrophy. TGF-β1 has been found to increase ASMC proliferation. The activation of mitogen-activated protein kinases (MAPKs), p38, ERK, and...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360679/ https://www.ncbi.nlm.nih.gov/pubmed/16390551 http://dx.doi.org/10.1186/1465-9921-7-2 |