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TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases

BACKGROUND: Airway remodeling in asthma is the result of increased expression of connective tissue proteins, airway smooth muscle cell (ASMC) hyperplasia and hypertrophy. TGF-β1 has been found to increase ASMC proliferation. The activation of mitogen-activated protein kinases (MAPKs), p38, ERK, and...

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Detalles Bibliográficos
Autores principales:	Chen, Gang, Khalil, Nasreen
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360679/ https://www.ncbi.nlm.nih.gov/pubmed/16390551 http://dx.doi.org/10.1186/1465-9921-7-2

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