Cargando…

Accurate quantification of DNA methylation using combined bisulfite restriction analysis coupled with the Agilent 2100 Bioanalyzer platform

DNA methylation is the best-studied epigenetic modification and describes the conversion of cytosine to 5-methylcytosine. The importance of this phenomenon is that aberrant promoter hypermethylation is a common occurrence in cancer and is frequently associated with gene silencing. Various techniques...

Descripción completa

Detalles Bibliográficos
Autores principales: Brena, Romulo Martin, Auer, Herbert, Kornacker, Karl, Hackanson, Björn, Raval, Aparna, Byrd, John C., Plass, Christoph
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361623/
https://www.ncbi.nlm.nih.gov/pubmed/16464820
http://dx.doi.org/10.1093/nar/gnj017