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Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea

BACKGROUND: Glioblastoma multiforme is the most malignant form of brain tumor. Despite treatment including surgical resection, adjuvant chemotherapy, and radiation, these tumors typically recur. The recurrent tumor is often resistant to further therapy with the same agent, suggesting that the surviv...

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Detalles Bibliográficos
Autores principales: Hank, Nicole C, Shapiro, Joan Rankin, Scheck, Adrienne C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361789/
https://www.ncbi.nlm.nih.gov/pubmed/16393339
http://dx.doi.org/10.1186/1471-2407-6-2