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Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNA

BACKGROUND: Haplosclerid marine sponges produce pore forming polyalkylpyridinium salts (poly-APS), which can be used to deliver macromolecules into cells. The aim of this study was to investigate the delivery of DNA, siRNA and lucifer yellow into cells mediated by poly-APS and its potential mechanis...

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Detalles Bibliográficos
Autores principales: McLaggan, Debra, Adjimatera, Noppadon, Sepčić, Kristina, Jaspars, Marcel, MacEwan, David J, Blagbrough, Ian S, Scott, Roderick H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361793/
https://www.ncbi.nlm.nih.gov/pubmed/16412248
http://dx.doi.org/10.1186/1472-6750-6-6