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Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNA
BACKGROUND: Haplosclerid marine sponges produce pore forming polyalkylpyridinium salts (poly-APS), which can be used to deliver macromolecules into cells. The aim of this study was to investigate the delivery of DNA, siRNA and lucifer yellow into cells mediated by poly-APS and its potential mechanis...
Autores principales: | McLaggan, Debra, Adjimatera, Noppadon, Sepčić, Kristina, Jaspars, Marcel, MacEwan, David J, Blagbrough, Ian S, Scott, Roderick H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361793/ https://www.ncbi.nlm.nih.gov/pubmed/16412248 http://dx.doi.org/10.1186/1472-6750-6-6 |
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