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Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi

BACKGROUND: Studies of gene function in the mouse have relied mainly on gene targeting via homologous recombination. However, this approach is difficult to apply in specific windows of time, and to simultaneously knock-down multiple genes. Here we report an efficient method for dsRNA-mediated gene s...

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Detalles Bibliográficos
Autores principales: Soares, Miguel L, Haraguchi, Seiki, Torres-Padilla, Maria-Elena, Kalmar, Tibor, Carpenter, Lee, Bell, Graham, Morrison, Alastair, Ring, Christopher JA, Clarke, Neil J, Glover, David M, Zernicka-Goetz, Magdalena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363358/
https://www.ncbi.nlm.nih.gov/pubmed/16381610
http://dx.doi.org/10.1186/1471-213X-5-28