DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion

HinP1I recognizes and cleaves the palindromic tetranucleotide sequence G↓CGC in DNA. We report three structures of HinP1I–DNA complexes: in the presence of Ca(2+) (pre-reactive complex), in the absence of metal ion (binary complex) and in the presence of Mg(2+) (post-reactive complex). HinP1I forms...

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Detalles Bibliográficos
Autores principales: Horton, John R., Zhang, Xing, Maunus, Robert, Yang, Zhe, Wilson, Geoffrey G., Roberts, Richard J., Cheng, Xiaodong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363774/
https://www.ncbi.nlm.nih.gov/pubmed/16473850
http://dx.doi.org/10.1093/nar/gkj484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363774/
https://www.ncbi.nlm.nih.gov/pubmed/16473850
http://dx.doi.org/10.1093/nar/gkj484

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