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DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion
HinP1I recognizes and cleaves the palindromic tetranucleotide sequence G↓CGC in DNA. We report three structures of HinP1I–DNA complexes: in the presence of Ca(2+) (pre-reactive complex), in the absence of metal ion (binary complex) and in the presence of Mg(2+) (post-reactive complex). HinP1I forms...
Autores principales: | Horton, John R., Zhang, Xing, Maunus, Robert, Yang, Zhe, Wilson, Geoffrey G., Roberts, Richard J., Cheng, Xiaodong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363774/ https://www.ncbi.nlm.nih.gov/pubmed/16473850 http://dx.doi.org/10.1093/nar/gkj484 |
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